Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

Zeneng Wang, Adam Roberts, Jennifer A. Buffa, +14

Cell

DysbiosisMedicineLipid PeroxidationNon-lethal InhibitionBiotechnology +7

An abundant dysfunctional apolipoprotein A1 in human atheroma

Ying Huang, Joseph A. DiDonato, Bruce S. Levison, +27

Nature Medicine

Human AtheromaVascular DiseasePathologyHyperlipidemiaVascular Biology +3

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

Wei Qi, Kehao Zhao, Justin Gu, +37

Nature Chemical Biology

Signal TransductionSignaling PathwayCell RegulationReceptor Tyrosine KinaseReceptor (Biochemistry) +5

Paradoxical Association of Enhanced Cholesterol Efflux With Increased Incident Cardiovascular Risks

Xin-Min Li, W.H. Wilson Tang, Marian Mosior, +9

Arteriosclerosis Thrombosis and Vascular Biology

Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

Ying Huang, Zhiping Wu, Meliana Riwanto, +21

Journal of Clinical Investigation

InflammationFunctional Ternary ComplexOxysterolAldo-keto ReductaseBiochemistry +13

Modification of High Density Lipoprotein by Myeloperoxidase Generates a Pro-inflammatory Particle

Arundhati Undurti, Ying Huang, Joseph A. Lupica, +3

Journal of Biological Chemistry

Apolipoprotein A1Lipid PeroxidationImmunologyHyperlipidemiaRedox Biology +15

A Facile System for Genetic Incorporation of Two Different Noncanonical Amino Acids into One Protein in <i>Escherichia coli</i>

Wei Wan, Ying Huang, Zhiyong Wang, +4

Angewandte Chemie International Edition

Regioselective Synthesis of 1,3,5-Triaryl-4-alkylpyrazoles:  Novel Ligands for the Estrogen Receptor

Ying Huang, John A. Katzenellenbogen

Organic Letters

Improving pea protein functionality by combining high-pressure homogenization with an ultrasound-assisted Maillard reaction

Sheliang Zhao, Ying Huang, David Julian McClements, +3

Food Hydrocolloids

EngineeringHigh-pressure HomogenizationPea Protein FunctionalityUltrasound-assisted Maillard ReactionBiochemical Engineering +9

Effects of Native and Myeloperoxidase-Modified Apolipoprotein A-I on Reverse Cholesterol Transport and Atherosclerosis in Mice

Bernd Hewing, Saj Parathath, Tessa J. Barrett, +13

Arteriosclerosis Thrombosis and Vascular Biology