Chang Park

Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity

Milan Bruncko, Le Wang, George S. Sheppard et al. · Journal of Medicinal Chemistry · 2015 · 150 citations · Full text

Drug Target, Mcl-1 Inhibitors, High Throughput +23

Discovery and Design of Novel HSP90 Inhibitors Using Multiple Fragment‐based Design Strategies

Jeffrey R. Huth, Chang Park, Andrew M. Petros et al. · Chemical Biology & Drug Design · 2007 · 118 citations · Full text

SOS-NMR:  A Saturation Transfer NMR-Based Method for Determining the Structures of Protein−Ligand Complexes

Philip J. Hajduk, J. Mack, Edward T. Olejniczak et al. · Journal of the American Chemical Society · 2004 · 90 citations

Nmr Methods, Biochemistry, Structural Bioinformatics +13

Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein

Andrew M. Petros, Steven L. Swann, Danying Song et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 80 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +10

Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

Gui‐Dong Zhu, Viraj B. Gandhi, Jianchun Gong et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 49 citations · Full text

Molecular Pharmacology, Oncology, Medicine +6