Jeffrey R. Huth

Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

Philip J. Hajduk, Jeffrey R. Huth, Stephen W. Fesik · Journal of Medicinal Chemistry · 2005 · 525 citations

Pharmacy, Bioinformatics, Medicinal Chemistry +17

Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex

Milton H. Werner, Jeffrey R. Huth, Angela M. Gronenborn et al. · Cell · 1995 · 468 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

The solution structure of an HMG-I(Y)–DNA complex defines a new architectural minor groove binding motif

Jeffrey R. Huth, Carole A. Bewley, M.S. Nissen et al. · Nature Structural Biology · 1997 · 410 citations

Life Sciences, Biophysics, Molecular Biology +14

Novel <i>p</i>-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties

Gang Liu, Jeffrey R. Huth, Edward T. Olejniczak et al. · Journal of Medicinal Chemistry · 2001 · 354 citations · Full text

Life Sciences, Immunology, Pharmacology +17

ALARM NMR:  A Rapid and Robust Experimental Method To Detect Reactive False Positives in Biochemical Screens

Jeffrey R. Huth, Renaldo Mendoza, Edward T. Olejniczak et al. · Journal of the American Chemical Society · 2004 · 231 citations

Pharmacy, Medicinal Chemistry, Drug Design +16