Stuart H. Johnston

Fringe is a glycosyltransferase that modifies Notch

Daniel J. Moloney, Vladislav M. Panin, Stuart H. Johnston et al. · Nature · 2000 · 846 citations

Life Sciences, Biochemistry, Molecular Biology +9

Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2

Carol Hicks, Stuart H. Johnston, Guy diSibio et al. · Nature Cell Biology · 2000 · 377 citations

Life Sciences, Cell Biology, Molecular Biology +8

A family of mammalian <i>Fringe</i> genes implicated in boundary determination and the <i>Notch</i> pathway

Stuart H. Johnston, Cordelia Rauskolb, Richa Wilson et al. · Development · 1997 · 297 citations

Life Sciences, Developmental Biology, Molecular Biology +14

Intermittent Administration of MEK Inhibitor GDC-0973 plus PI3K Inhibitor GDC-0941 Triggers Robust Apoptosis and Tumor Growth Inhibition

Klaus P. Hoeflich, Mark Merchant, Christine Orr et al. · Cancer Research · 2011 · 244 citations · Full text

Medicine, Oncology, Pharmacology +17

Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)

Kenneth D. Rice, Naing Aay, Neel K. Anand et al. · ACS Medicinal Chemistry Letters · 2012 · 168 citations · Full text

Medicine, Oncology, Pharmacology +14