Klaus P. Hoeflich

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Mapk Pathway +8

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

Klaus P. Hoeflich, Juan Luo, Elizabeth A. Rubie et al. · Nature · 2000 · 1.4K citations

Signal Transduction, Signaling Pathway, Molecular Pathway +11

A Central Role for HER3 in <i>HER2</i> -Amplified Breast Cancer: Implications for Targeted Therapy

Si Tuen Lee-Hoeflich, Lisa Crocker, Evelyn Yao et al. · Cancer Research · 2008 · 642 citations · Full text

MazF Cleaves Cellular mRNAs Specifically at ACA to Block Protein Synthesis in Escherichia coli

Yonglong Zhang, Junjie Zhang, Klaus P. Hoeflich et al. · Molecular Cell · 2003 · 550 citations · Full text

Protein Expression, Natural Sciences, Protein Biosynthesis +10

<i>In vivo</i> Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models

Klaus P. Hoeflich, Carol O’Brien, Zachary Boyd et al. · Clinical Cancer Research · 2009 · 470 citations