Karen Miller

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 948 citations · Full text

Selective Small-molecule Inhibitor, Signal Transduction, Signaling Pathway +11

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 628 citations

Protein Function, Signal Transduction, Cell Regulation +10

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs

Philip P. Chamberlain, Antonia Lopez‐Girona, Karen Miller et al. · Nature Structural & Molecular Biology · 2014 · 499 citations

Molecular Pharmacology, Natural Sciences, Molecular Biology +6

A central role for astrocytes in the inflammatory response to β-amyloid; chemokines, cytokines and reactive oxygen species are produced

Mandy Johnstone, A. J. H. Gearing, Karen Miller · Journal of Neuroimmunology · 1999 · 312 citations

Inflammation, Central Role, Medicine +13

Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke

Daniel C. Anthony, Betsy Ferguson, M.K. Matyzak et al. · Neuropathology and Applied Neurobiology · 1997 · 266 citations

Tissue Destruction, Neurological Disorder, Immunology +18