Concepedia

Philip P. Chamberlain

PP

Statistics

Publications

29

Citations

4.7K

H-Index

26

Active since

2001

Affiliations

Centre for Human Genetics(Current)

University of Oxford

Bristol-Myers Squibb (United States)

Bristol-Myers Squibb (Switzerland)

Dana-Farber Cancer Institute

Philip P. Chamberlain is an author at Centre for Human Genetics specializing in molecular biology, life sciences, and cell signaling.

ORCID

Publications per year

2001–2022

29

Publications

29

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

Jan Krönke, Emma C. Fink, Paul W. Hollenbach et al. · Nature · 2015 · 836 citations · Full text

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A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 670 citations

, , +11

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs

Philip P. Chamberlain, Antonia Lopez‐Girona, Karen Miller et al. · Nature Structural & Molecular Biology · 2014 · 515 citations

, , +5

SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate

Mary E. Matyskiela, Suzana S. Couto, Xinde Zheng et al. · Nature Chemical Biology · 2018 · 343 citations

, , +5

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Mary E. Matyskiela, Weihong Zhang, Hon‐Wah Man et al. · Journal of Medicinal Chemistry · 2017 · 291 citations · Full text

, , +13

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