Concepedia

Mary E. Matyskiela

ME

22

Publications

3.5K

Citations

21

H-Index

2001

Active since

Affiliations

Scripps Research Institute(Current)

University of California, Berkeley

Merck & Co., Inc., Rahway, NJ, USA (United States)

University of California, San Francisco

QB3

Mary E. Matyskiela is an author at Scripps Research Institute specializing in natural sciences, molecular biology, and biochemistry.

Top concepts

Natural SciencesBiochemistryMolecular BiologyMedicineProtein AssemblyProteomicsSignal TransductionProteasomeIon ChannelsPharmacology

Publications per year

2001–2022

22

Publications

22

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 628 citations

Protein Function, Signal Transduction, Cell Regulation +10

Complete subunit architecture of the proteasome regulatory particle

Gabriel C. Lander, Eric Estrin, Mary E. Matyskiela et al. · Nature · 2012 · 615 citations

Protein Function, Biochemistry, Protein Assembly +6

SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate

Mary E. Matyskiela, Suzana S. Couto, Xinde Zheng et al. · Nature Chemical Biology · 2018 · 327 citations

Mutagenesis, Thalidomide-dependent Cereblon Substrate, Biochemistry

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Mary E. Matyskiela, Weihong Zhang, Hon‐Wah Man et al. · Journal of Medicinal Chemistry · 2017 · 283 citations · Full text

Conformational switching of the 26S proteasome enables substrate degradation

Mary E. Matyskiela, Gabriel C. Lander, Andreas Martin · Nature Structural & Molecular Biology · 2013 · 265 citations · Full text

Protein Chemistry, Protein Assembly, Protein Folding +8

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