Takashi Shimada

Epidemiologic studies of stroke in Shibata, a Japanese provincial city: preliminary report on risk factors for cerebral infarction.

Heizo Tanaka, Masayuki Hayashi, Chigusa Date et al. · Stroke · 1985 · 99 citations

Medicine, Internal Medicine, Neurology +13

The modified light/dark transition test in mice: Evaluation of classic and putative anxiolytic and anxiogenic drugs

Takashi Shimada, Kinzo Matsumoto, Miyuki Osanai et al. · General Pharmacology The Vascular System · 1995 · 99 citations

Medicine, Pharmacology, Behavioral Pharmacology +9

Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity

Junya Kawai, Tadashi Toki, Masahiro Ota et al. · Journal of Medicinal Chemistry · 2019 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and Conformational Analysis of a Non-Amidine Factor Xa Inhibitor That Incorporates 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-<i>c</i>]pyridine as S4 Binding Element

Noriyasu Haginoya, Syozo Kobayashi, Satoshi Komoriya et al. · Journal of Medicinal Chemistry · 2004 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold

Junya Kawai, Masahiro Ota, Hitoshi Ohki et al. · ACS Medicinal Chemistry Letters · 2019 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8