Masanori Kobayashi

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Kendra E. Hightower, Ruolan Wang, Felix Deanda et al. · Antimicrobial Agents and Chemotherapy · 2011 · 221 citations

Immunology, Molecular Biology, Slower Dissociation +18

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 181 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15

TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy

Yu Matsuzawa, Shigeru Oshima, Masahiro Takahara et al. · Autophagy · 2015 · 135 citations · Full text

Immunology, Immune Regulation, Cell Death +18

The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development

Masanori Kobayashi, Shigeru Oshima, Chiaki Maeyashiki et al. · Scientific Reports · 2016 · 120 citations · Full text

Protein Function, Developmental Biology, Cell Regulation +13

Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants

Masanori Kobayashi, Koichiro Nakahara, Takahiro Seki et al. · Antiviral Research · 2008 · 104 citations

Human Retrovirus, Immunology, Antiviral Drug Development +8