Jing Shan Lim

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

Jing Shan Lim, Alvaro Ibaseta, Marcus Fischer et al. · Nature · 2017 · 482 citations · Full text

Medicine, Intratumoural Heterogeneity, Radiation Oncology +5

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

Kipp Weiskopf, Nadine S. Jahchan, Peter J. Schnorr et al. · Journal of Clinical Investigation · 2016 · 421 citations · Full text

Immune Evasion, Cd47-blocking Immunotherapies, Cancer Immunosurveillance +14

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

Sarah K. Denny, Dian Yang, Chen-Hua Chuang et al. · Cell · 2016 · 383 citations · Full text

Tumor Biology, Chromatin, Chromatin Accessibility +8

Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

David J. Wooten, Sarah M. Groves, Darren R. Tyson et al. · PLoS Computational Biology · 2019 · 113 citations · Full text

Engineering, Subtype Gene Signatures, Gene Regulatory Network +18

Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer

Sarah M. Groves, Geena V. Ildefonso, Caitlin O. McAtee et al. · Cell Systems · 2022 · 55 citations · Full text

Intratumoral Heterogeneity, Lineage Plasticity, Tumor Heterogeneity +13