Darren R. Tyson

Quantifying Drug Combination Synergy along Potency and Efficacy Axes

Christian T. Meyer, David J. Wooten, B. Bishal Paudel et al. · Cell Systems · 2019 · 215 citations

Drug Combination Synergy, Substance Abuse, Addiction +4

Parathyroid Hormone Regulation of the Rat Collagenase-3 Promoter by Protein Kinase A-dependent Transactivation of Core Binding Factor α1

N. Selvamurugan, Malini R. Pulumati, Darren R. Tyson et al. · Journal of Biological Chemistry · 2000 · 188 citations · Full text

Periprostatic Adipose Tissue as a Modulator of Prostate Cancer Aggressiveness

David S. Finley, Valerie Calvert, Junichi Inokuchi et al. · The Journal of Urology · 2009 · 138 citations

Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data

Darren R. Tyson, Shawn Garbett, Peter L. Frick et al. · Nature Methods · 2012 · 115 citations · Full text

Single-cell Data, Cell Division, Single Cell Sequencing +9

Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

David J. Wooten, Sarah M. Groves, Darren R. Tyson et al. · PLoS Computational Biology · 2019 · 113 citations · Full text

Engineering, Subtype Gene Signatures, Gene Regulatory Network +18