Darren R. Tyson

Quantifying Drug Combination Synergy along Potency and Efficacy Axes

Christian T. Meyer, David J. Wooten, B. Bishal Paudel et al. · Cell Systems · 2019 · 231 citations

Medicine, Pharmacology, Pharmacotherapy +13

Parathyroid Hormone Regulation of the Rat Collagenase-3 Promoter by Protein Kinase A-dependent Transactivation of Core Binding Factor α1

N. Selvamurugan, Malini R. Pulumati, Darren R. Tyson et al. · Journal of Biological Chemistry · 2000 · 188 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Periprostatic Adipose Tissue as a Modulator of Prostate Cancer Aggressiveness

David S. Finley, Valerie Calvert, Junichi Inokuchi et al. · The Journal of Urology · 2009 · 140 citations

Medicine, Oncology, Urology +11

Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

David J. Wooten, Sarah M. Groves, Darren R. Tyson et al. · PLoS Computational Biology · 2019 · 119 citations · Full text

Life Sciences, Oncology, Systems Biology +17

Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data

Darren R. Tyson, Shawn Garbett, Peter L. Frick et al. · Nature Methods · 2012 · 115 citations · Full text

Life Sciences, Biology, Cell Biology +12