Yang Xu

Intestinal and Hepatic CYP3A4 Catalyze Hydroxylation of 1α,25-Dihydroxyvitamin D3: Implications for Drug-Induced Osteomalacia

Yang Xu, Takanori Hashizume, Margaret C. Shuhart et al. · Molecular Pharmacology · 2005 · 171 citations

Medicine, Pharmacology, Bone Metabolism +16

Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction

Magang Shou, Mike Hayashi, Yvonne Pan et al. · Drug Metabolism and Disposition · 2008 · 132 citations

Medicine, Pharmacokinetics, Pharmacology +17

Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors

Noel D. D’Angelo, Tae‐Seong Kim, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2011 · 119 citations · Full text

Pharmacy, Oncology, Pharmacology +14

Discovery of AMG 369, a Thiazolo[5,4-<i>b</i>]pyridine Agonist of S1P₁ and S1P₅

Victor J. Cee, Mike Frohn, Brian A. Lanman et al. · ACS Medicinal Chemistry Letters · 2010 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs

Yang Xu, Yihong Zhou, Mike Hayashi et al. · Drug Metabolism and Disposition · 2011 · 47 citations

Pharmacy, Pharmacokinetics, Pharmacology +17