Mike Hayashi

Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction

Magang Shou, Mike Hayashi, Yvonne Pan et al. · Drug Metabolism and Disposition · 2008 · 132 citations

Simulation of Clinical Drug-Drug Interactions from Hepatocyte CYP3A4 Induction Data and Its Potential Utility in Trial Designs

Yang Xu, Yihong Zhou, Mike Hayashi et al. · Drug Metabolism and Disposition · 2011 · 47 citations

Albumin-Mediated Uptake Improves Human Clearance Prediction for Hepatic Uptake Transporter Substrates Aiding a Mechanistic In Vitro-In Vivo Extrapolation (IVIVE) Strategy in Discovery Research

Na Li, Akshay Badrinarayanan, Kazuya Ishida et al. · The AAPS Journal · 2020 · 37 citations

Vitro-in Vivo Extrapolation, Translational Medicine, Hepatology +11

Comparison of In Vitro to In Vivo Extrapolation Approaches for Predicting Transporter-Mediated Hepatic Uptake Clearance Using Suspended Rat Hepatocytes

Na Li, Akshay Badrinarayanan, Xingwen Li et al. · Drug Metabolism and Disposition · 2020 · 20 citations · Full text

In Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in Humans

Chun Li, Mita Kuchimanchi, Dean Hickman et al. · Drug Metabolism and Disposition · 2009 · 15 citations