Jin‐Peng Sun

Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

Thomas J. Cahill, A. Thomsen, Jeffrey Tarrasch et al. · Proceedings of the National Academy of Sciences · 2017 · 374 citations · Full text

Molecular Regulation, Molecular Biology, Tail Conformation +18

Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury

Tuoyi Li, Bing Yu, Zhixin Liu et al. · Nature Communications · 2017 · 254 citations · Full text

Multiple ligand-specific conformations of the β2-adrenergic receptor

Alem W. Kahsai, Kunhong Xiao, Sudarshan Rajagopal et al. · Nature Chemical Biology · 2011 · 248 citations · Full text

Molecular Pharmacology, Signal Transduction, Molecular Physiology +9

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design

Shaoyong Lu, Xinheng He, Zhao Yang et al. · Nature Communications · 2021 · 214 citations · Full text

Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and 19F-NMR

Fan Yang, Xiao Yu, Chuan Liu et al. · Nature Communications · 2015 · 198 citations · Full text