Thomas J. Cahill

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

A. Thomsen, Bianca Plouffe, Thomas J. Cahill et al. · Cell · 2016 · 553 citations · Full text

Protein Function, Signal Transduction, Molecular Physiology +8

Drug Release from Electric-Field-Responsive Nanoparticles

Jun Ge, Evgenios Neofytou, Thomas J. Cahill et al. · ACS Nano · 2011 · 512 citations

Nanoparticles, Nanomedicine, Engineering +12

Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

Thomas J. Cahill, A. Thomsen, Jeffrey Tarrasch et al. · Proceedings of the National Academy of Sciences · 2017 · 374 citations · Full text

Molecular Regulation, Molecular Biology, Tail Conformation +18

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

Houman Ashrafian, Gábor Czibik, Mohamed Bellahcene et al. · Cell Metabolism · 2012 · 300 citations · Full text

Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex

Anthony H. Nguyen, A. Thomsen, Thomas J. Cahill et al. · Nature Structural & Molecular Biology · 2019 · 218 citations · Full text

Protein Function, G Protein-coupled Receptor, Cellular Biochemistry +4