Zhao Yang

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design

Shaoyong Lu, Xinheng He, Zhao Yang et al. · Nature Communications · 2021 · 214 citations · Full text

Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex

Yu-Qi Ping, Chunyou Mao, Peng Xiao et al. · Nature · 2021 · 172 citations · Full text

Signal Transduction, G Protein-coupled Receptor, Cell Adhesion +5

Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4

Peng Xiao, Shengchao Guo, Xin Wen et al. · Nature · 2022 · 134 citations

Signal Transduction, Biochemistry, Adhesion Gpcrs Adgrg2 +5

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility

Daolai Zhang, Yujing Sun, Ming‐liang Ma et al. · eLife · 2018 · 84 citations · Full text

Fertility, Reproductive Biology, Ph Homeostasis +19

Mouse and Human Eosinophils Degranulate in Response to Platelet-Activating Factor (PAF) and LysoPAF via a PAF-Receptor–Independent Mechanism: Evidence for a Novel Receptor

Kimberly D. Dyer, Caroline M. Percopo, Zhihui Xie et al. · The Journal of Immunology · 2010 · 82 citations · Full text

Immunology, Cell Death, Immunologic Mechanism +22