Shengchao Guo

Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4

Peng Xiao, Shengchao Guo, Xin Wen et al. · Nature · 2022 · 134 citations

Signal Transduction, Biochemistry, Adhesion Gpcrs Adgrg2 +5

Structural basis for the tethered peptide activation of adhesion GPCRs

Yu-Qi Ping, Peng Xiao, Fan Yang et al. · Nature · 2022 · 125 citations

Biochemistry, Cell Adhesion, Adhesive Material +3

Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury

Yi Fu, Yaqian Huang, Zhao Yang et al. · Cell Research · 2021 · 57 citations · Full text

Structures of the ADGRG2–Gs complex in apo and ligand-bound forms

Hui Lin, Peng Xiao, Ruiqian Bu et al. · Nature Chemical Biology · 2022 · 45 citations

Biochemistry, Natural Sciences, Molecular Biology +3

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1H-NMR probe

Qi Liu, Qing‐tao He, Xiaoxuan Lyu et al. · Nature Communications · 2020 · 37 citations · Full text