Hui Lin

Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4

Peng Xiao, Shengchao Guo, Xin Wen et al. · Nature · 2022 · 134 citations

Signal Transduction, Biochemistry, Adhesion Gpcrs Adgrg2 +5

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility

Daolai Zhang, Yujing Sun, Ming‐liang Ma et al. · eLife · 2018 · 84 citations · Full text

Fertility, Reproductive Biology, Ph Homeostasis +19

Gypenosides induced G0/G1 arrest via inhibition of cyclin E and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells.

Hsu Feng Lu, Yi Shan Chen, Jai‐Sing Yang et al. · PubMed · 2008 · 73 citations

Chemoprevention Strategy, Gynostemma Pentaphyllum Makino, Apoptosis +17

Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression.

Hui Lin, Chin Cheng Su, Hsu Feng Lu et al. · PubMed · 2010 · 63 citations

Chemoprevention Strategy, Cancer Metastasis, Cellular Physiology +20

Progesterone activates GPR126 to promote breast cancer development via the Gi pathway

Wentao An, Hui Lin, Lijuan Ma et al. · Proceedings of the National Academy of Sciences · 2022 · 48 citations · Full text

Breast Oncology, Agpcr Member Gpr126, Gynecology +20