Guoping Wang

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of Medicinal Chemistry · 2006 · 681 citations · Full text

Combinatorial Chemistry, Mdm2-p53 Interaction, Chemoprevention Strategy +19

Potent and Orally Active Small-Molecule Inhibitors of the MDM2−p53 Interaction

Shanghai Yu, Dongguang Qin, Sanjeev Shangary et al. · Journal of Medicinal Chemistry · 2009 · 176 citations · Full text

Preclinical Studies of TW-37, a New Nonpeptidic Small-Molecule Inhibitor of Bcl-2, in Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action on Both Bcl-2 and Mcl-1

Ramzi M. Mohammad, Anton Scott Goustin, Amro Aboukameel et al. · Clinical Cancer Research · 2007 · 148 citations

Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer

Sanjeev Shangary, Ke Ding, Su Qiu et al. · Molecular Cancer Therapeutics · 2008 · 90 citations · Full text

P53 Status, P53 Dependent, Cell Death +18

Synthesis, Crystal Structure, Stacking Effect and Antibacterial Studies of a Novel Quaternary Copper (II) Complex with Quinolone

Guangguo Wu, Guoping Wang, Xu-Chun Fu et al. · Molecules · 2003 · 67 citations · Full text

Inorganic Chemistry, Crystal Structure, Biochemistry +13