Concepedia

Author

Zhe Li

Global Blood Therapeutics (United States)ORCID

Also Known As

Zhe Li

19

Publications

750

Citations

14

H-Index

28

Concepts

All Affiliations

Global Blood Therapeutics (United States)University of California, San FranciscoInstitute for Neurodegenerative DisordersAlbert Einstein College of MedicinePfizer (United States)
ZL

About

Zhe Li is an author at Global Blood Therapeutics (United States) specializing in biochemistry, medicine, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

299

2

Biochemistry

4

4

92

3

Natural Sciences

2

2

41

4

Cell Biology

2

2

257

5

Chemical Biology

2

2

41

Zhe Li

×

14

Publications

740

Citations

14

H-Index

YearCitations

<scp>GBT</scp>440 increases haemoglobin oxygen affinity, reduces sickling and prolongs <scp>RBC</scp> half‐life in a murine model of sickle cell disease

Donna Oksenberg, Kobina Dufu, Mira Patel,

British Journal of Haematology

2016

232

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu,

ACS Medicinal Chemistry Letters

2017

183

Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors

Alexey Dementiev, Abel Silva, Calvin Yee,

Blood Advances

2018

52

Biaryl Amides and Hydrazones as Therapeutics for Prion Disease in Transgenic Mice

Duo Lü, Kurt Giles, Zhe Li,

Journal of Pharmacology and Experimental Therapeutics

2013

45

Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors

Zhe Li, James R. Partridge, Abel Silva‐Garcia,

ACS Medicinal Chemistry Letters

2016

34

GBT1118, a potent allosteric modifier of hemoglobin O<sub>2</sub>affinity, increases tolerance to severe hypoxia in mice

Kobina Dufu, Özlem Yalçın, Eilleen S. Y. Ao-ieong,

American Journal of Physiology-Heart and Circulatory Physiology

2017

32

Pharmacokinetics and Metabolism of 2-Aminothiazoles with Antiprion Activity in Mice

B. Michael Silber, Satish Rao, Kimberly L. Fife,

Pharmaceutical Research

2013

31

Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells

B. Michael Silber, Joel R. Gever, Satish Rao,

Bioorganic & Medicinal Chemistry

2014

25

Antiprion compounds that reduce PrPSc levels in dividing and stationary-phase cells

B. Michael Silber, Joel R. Gever, Zhe Li,

Bioorganic & Medicinal Chemistry

2013

20

2‐Aminothiazoles with Improved Pharmacotherapeutic Properties for Treatment of Prion Disease

Zhe Li, B. Michael Silber, Satish Rao,

ChemMedChem

2013

20

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