Concepedia

James R. Partridge

JR

11

Publications

674

Citations

11

H-Index

2009

Active since

Affiliations

Global Blood Therapeutics (United States)(Current)

University of California, San Francisco

Massachusetts Institute of Technology

Howard Hughes Medical Institute

James R. Partridge is an author at Global Blood Therapeutics (United States) specializing in natural sciences, molecular biology, and biochemistry.

ORCID

Top concepts

Publications per year

2009–2023

11

Publications

11

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu et al. · ACS Medicinal Chemistry Letters · 2017 · 183 citations · Full text

Structural Asymmetry in the Closed State of Mitochondrial Hsp90 (TRAP1) Supports a Two-Step ATP Hydrolysis Mechanism

Laura A. Lavery, James R. Partridge, Theresa A. Ramelot et al. · Molecular Cell · 2014 · 159 citations · Full text

, , +9

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities

Renuka K. Pandya, James R. Partridge, Kerry R. Love et al. · Journal of Biological Chemistry · 2009 · 68 citations · Full text

, , +14

Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors

Alexey Dementiev, Abel Silva, Calvin Yee et al. · Blood Advances · 2018 · 52 citations · Full text

Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain

James R. Partridge, Thomas Schwartz · Journal of Molecular Biology · 2009 · 51 citations · Full text

, , +7

Rows per page

1–5 of 11