Hironobu Maezaki

Anti‐tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC‐dependent vulnerability

Kenichi Iwai, Masahiro Yaguchi, Kazuho Nishimura et al. · EMBO Molecular Medicine · 2018 · 89 citations · Full text

Computational studies on CH/? interactions

Tatsuya Takagi, Akito Tanaka, Sanshiro Matsuo et al. · Journal of the Chemical Society Perkin Transactions 2 · 1987 · 63 citations

Engineering, Ch/π Systems, Natural Sciences +15

Discovery of 3-Benzyl-1-(<i>trans</i>-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors

Masahiro Ito, Toshio Tanaka, Akinori Toita et al. · Journal of Medicinal Chemistry · 2018 · 60 citations · Full text

Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor

Yasufumi Miyamoto, Yoshihiro Banno, Tatsuhiko Fujimoto et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Pharmacotherapy +16

Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554

Yoshihiro Banno, Yasufumi Miyamoto, Mitsuru Sasaki et al. · Bioorganic & Medicinal Chemistry · 2011 · 42 citations · Full text

Medicinal Chemistry, Unique Interaction, Bioorganic Chemistry +10