Akito Tanaka

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

Ryohei Furumai, Akihisa Matsuyama, Nobuyuki Kobashi et al. · PubMed · 2002 · 744 citations

Reductive Stress, Disulfide Bond, Biochemistry +15

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

K Ohnishi, Katsunori Semi, Takuya Yamamoto et al. · Cell · 2014 · 446 citations · Full text

Chromatin, Altered Epigenetic Regulation, Vivo Leads +10

Selective degradation of splicing factor CAPERα by anticancer sulfonamides

Taisuke Uehara, Yukinori Minoshima, Koji Sagane et al. · Nature Chemical Biology · 2017 · 366 citations

Medicinal Chemistry, Medicine, Natural Sciences +6

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis

Keiko Imamura, Yuishin Izumi, Akira Watanabe et al. · Science Translational Medicine · 2017 · 249 citations · Full text

Derivation of ground-state female ES cells maintaining gamete-derived DNA methylation

Masaki Yagi, Satoshi Kishigami, Akito Tanaka et al. · Nature · 2017 · 205 citations

Gamete-derived Dna Methylation, Chromatin, Somatic Cell Genetics +8