Hiroaki Suzuki

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi et al. · Nature Medicine · 2007 · 535 citations

Obesity, Metabolic Syndrome, Biochemistry +10

SREBPs suppress IRS-2-mediated insulin signalling in the liver

Tomohiro Ide, Hitoshi Shimano, Naoya Yahagi et al. · Nature Cell Biology · 2004 · 315 citations

Metabolic Syndrome, Signal Transduction, Hepatology +8

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

Yoshimi Nakagawa, Hitoshi Shimano, Tomohiro Yoshikawa et al. · Nature Medicine · 2005 · 207 citations

Metabolic Syndrome, Transcriptional Regulation, Systems Biology +13

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

Noriko Nakanishi, Yoshimi Nakagawa, Naoko Tokushige et al. · Biochemical and Biophysical Research Communications · 2009 · 181 citations

Obesity, Metabolic Syndrome, Lipid Metabolism +13

SREBP-1 Interacts with Hepatocyte Nuclear Factor-4α and Interferes with PGC-1 Recruitment to Suppress Hepatic Gluconeogenic Genes

Takashi Yamamoto, Hitoshi Shimano, Yoshimi Nakagawa et al. · Journal of Biological Chemistry · 2004 · 141 citations · Full text