David M. Dias

Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

Carles Galdeano, Morgan S. Gadd, Pedro Soares et al. · Journal of Medicinal Chemistry · 2014 · 392 citations · Full text

Protein Function, Biochemistry, Natural Sciences +13

Local unfolding of the HSP27 monomer regulates chaperone activity

T. Reid Alderson, Julien Roche, Heidi Y. Gastall et al. · Nature Communications · 2019 · 107 citations · Full text

Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein–Protein Interactions?

David M. Dias, Inge Van Molle, Matthias G. J. Baud et al. · ACS Medicinal Chemistry Letters · 2013 · 53 citations · Full text

Protein–protein Interactions, Saturation Transfer Difference, Drug Target +28

Fragment-Based Design of <i>Mycobacterium tuberculosis</i> InhA Inhibitors

Mohamad Sabbah, V. Mendes, Robert G. Vistal et al. · Journal of Medicinal Chemistry · 2020 · 48 citations · Full text

Fragment-based Design, Pulmonary Tuberculosis, Antimicrobial Drug Discovery +14

Interaction of PiB‐Derivative Metal Complexes with Beta‐Amyloid Peptides: Selective Recognition of the Aggregated Forms

André F. Martins, David M. Dias, Jean‐François Morfin et al. · Chemistry - A European Journal · 2015 · 31 citations