Heidi Y. Gastall

Phosphomimics Destabilize Hsp27 Oligomeric Assemblies and Enhance Chaperone Activity

Blagojce Jovcevski‬, Megan A. Kelly, Anthea P. Rote et al. · Chemistry & Biology · 2015 · 127 citations

Protein Chemistry, Biochemistry, Protein Assembly +4

Local unfolding of the HSP27 monomer regulates chaperone activity

T. Reid Alderson, Julien Roche, Heidi Y. Gastall et al. · Nature Communications · 2019 · 107 citations · Full text

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C

M Collier, T. Reid Alderson, Carin P. de Villiers et al. · Science Advances · 2019 · 72 citations · Full text

A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins

T. Reid Alderson, Elias Adriaenssens, Bob Asselbergh et al. · The EMBO Journal · 2021 · 25 citations · Full text