Inge Van Molle

Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

Dennis L. Buckley, Inge Van Molle, Peter C. Gareiss et al. · Journal of the American Chemical Society · 2012 · 540 citations · Full text

Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

Carles Galdeano, Morgan S. Gadd, Pedro Soares et al. · Journal of Medicinal Chemistry · 2014 · 392 citations · Full text

Protein Function, Biochemistry, Natural Sciences +13

Small‐Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

Dennis L. Buckley, Jeffrey L. Gustafson, Inge Van Molle et al. · Angewandte Chemie International Edition · 2012 · 280 citations · Full text

Secreted amyloid-β precursor protein functions as a GABA _B R1a ligand to modulate synaptic transmission

Heather C. Rice, Daniel de Malmazet, An Schreurs et al. · Science · 2019 · 261 citations · Full text

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

Inge Van Molle, Andreas Thomann, Dennis L. Buckley et al. · Chemistry & Biology · 2012 · 190 citations · Full text

Protein Function, Protein Assembly, Biochemistry +12