Steffen Renner

Small-molecule inhibition of APT1 affects Ras localization and signaling

Frank J. Dekker, Oliver Rocks, Nachiket Vartak et al. · Nature Chemical Biology · 2010 · 393 citations

Signal Transduction, Signaling Pathway, G Protein-coupled Receptor +6

Natural-product-derived fragments for fragment-based ligand discovery

Björn Over, Stefan Wetzel, Christian Grütter et al. · Nature Chemistry · 2012 · 299 citations

Combinatorial Chemistry, Biochemistry, Medicine +3

DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

Chaoyang Ye, Daniel Ho, Marilisa Neri et al. · Nature Communications · 2018 · 231 citations · Full text

Interactive exploration of chemical space with Scaffold Hunter

Stefan Wetzel, Karsten Klein, Steffen Renner et al. · Nature Chemical Biology · 2009 · 228 citations

Scientific Visualization, Design, Chemistry +2

Scaffold‐Hopping: How Far Can You Jump?

Gisbert Schneider, Petra Schneider, Steffen Renner · QSAR & Combinatorial Science · 2006 · 147 citations

Current Scaffold‐hopping Strategies, Hit Identification, Movement Biomechanics +23