Christian Grütter

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Martin Peifer, Lynnette Fernandez‐Cuesta, Martin L. Sos et al. · Nature Genetics · 2012 · 1.4K citations · Full text

Engineering, Somatic Variant, Tumor Heterogeneity +10

The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing

Stéphanie Papin, Solange Cuenin, Laetitia Agostini et al. · Cell Death and Differentiation · 2007 · 309 citations

Inflammation, Spry Domain, Disease Mechanism +10

Natural-product-derived fragments for fragment-based ligand discovery

Björn Over, Stefan Wetzel, Christian Grütter et al. · Nature Chemistry · 2012 · 299 citations

Combinatorial Chemistry, Biochemistry, Medicine +3

ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors

Johannes M. Heuckmann, Michael Hölzel, Martin L. Sos et al. · Clinical Cancer Research · 2011 · 187 citations · Full text

Development of a Fluorescent-Tagged Kinase Assay System for the Detection and Characterization of Allosteric Kinase Inhibitors

Jeffrey R. Simard, Matthäus Getlik, Christian Grütter et al. · Journal of the American Chemical Society · 2009 · 146 citations