Concepedia

Author

Björn Over

AstraZeneca (Sweden)ORCID

Also Known As

Björn Over, Bjӧrn Over, Over, Björn

12

Publications

2K

Citations

9

H-Index

29

Concepts

All Affiliations

AstraZeneca (Sweden)Uppsala UniversityScience for Life LaboratoryMax Planck SocietyChemical Genomics Centre
BO

About

Björn Over is an author at AstraZeneca (Sweden) specializing in medicine, drug discovery, and biochemistry.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

5

5

670

2

Biochemistry

4

4

463

3

Engineering

1

1

85

4

Natural Sciences

1

1

26

5

Biomolecular Engineering

1

1

85

Björn Over

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7

Publications

923

Citations

7

H-Index

YearCitations

Natural-product-derived fragments for fragment-based ligand discovery

Björn Over, Stefan Wetzel, Christian Grütter,

Nature Chemistry

2012

299

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Matteo Rossi Sebastiano, B.C. Doak, Maria Backlund,

Journal of Medicinal Chemistry

2018

208

Structural and conformational determinants of macrocycle cell permeability

Björn Over, Pär Matsson, Christian Tyrchan,

Nature Chemical Biology

2016

207

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

Björn Over, Patrick McCarren, Per Artursson,

Journal of Medicinal Chemistry

2014

85

Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B

Viktor V. Vintonyak, Karin Warburg, Björn Over,

Tetrahedron

2011

53

Mining Natural Products for Macrocycles to Drug Difficult Targets

Fabio Begnini, Vasanthanathan Poongavanam, Björn Over,

Journal of Medicinal Chemistry

2020

45

Fragment‐Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition

Lisa Englert, Katrin Silber, H. Steuber,

ChemMedChem

2010

26

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