Björn Over

Natural-product-derived fragments for fragment-based ligand discovery

Björn Over, Stefan Wetzel, Christian Grütter et al. · Nature Chemistry · 2012 · 299 citations

Combinatorial Chemistry, Biochemistry, Medicine +3

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Matteo Rossi Sebastiano, B.C. Doak, Maria Backlund et al. · Journal of Medicinal Chemistry · 2018 · 208 citations · Full text

Structural and conformational determinants of macrocycle cell permeability

Björn Over, Pär Matsson, Christian Tyrchan et al. · Nature Chemical Biology · 2016 · 207 citations

Membrane Transport, Cytoskeleton, Cellular Structure +7

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

Björn Over, Patrick McCarren, Per Artursson et al. · Journal of Medicinal Chemistry · 2014 · 85 citations · Full text

Pharmaceutical Science, Engineering, Pharmaceutical Chemistry +22

Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B

Viktor V. Vintonyak, Karin Warburg, Björn Over et al. · Tetrahedron · 2011 · 53 citations

Pulmonary Tuberculosis, Biochemistry, Medicine +6