B.C. Doak

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Matteo Rossi Sebastiano, B.C. Doak, Maria Backlund et al. · Journal of Medicinal Chemistry · 2018 · 223 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structural and conformational determinants of macrocycle cell permeability

Björn Over, Pär Matsson, Christian Tyrchan et al. · Nature Chemical Biology · 2016 · 213 citations

Life Sciences, Biochemistry, Cell Biology +14

Application of Fragment‐Based Screening to the Design of Inhibitors of <i>Escherichia coli</i> DsbA

Luke A. Adams, Pooja Sharma, Biswaranjan Mohanty et al. · Angewandte Chemie International Edition · 2014 · 62 citations

Life Sciences, Biochemistry, Microbiology +17

Diffraction and imaging from a beam of laser-aligned proteins: resolution limits

J.C.H. Spence, K. E. Schmidt, J. Wu et al. · Acta Crystallographica Section A Foundations of Crystallography · 2005 · 60 citations

Life Sciences, Biology, Biophysics +15

Synthesis of Unsymmetrical 1,1′-Disubstituted Bis(1,2,3-triazole)s Using Monosilylbutadiynes

B.C. Doak, M.J. Scanlon, Jamie S. Simpson · Organic Letters · 2011 · 48 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14