Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B

Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Richard A. Friesner, Jay L. Banks, Robert B. Murphy et al. · Journal of Medicinal Chemistry · 2004 · 9.9K citations

Life Sciences, Biophysics, Medicinal Chemistry +17

Enzymes: a practical introduction to structure, mechanism, and data analysis

Choice Reviews Online · 2001 · 1.1K citations

Life Sciences, Biochemistry, Chemistry +17

Halogen Bonding—A Novel Interaction for Rational Drug Design?

Yunxiang Lu, Ting Shi, Yong Wang et al. · Journal of Medicinal Chemistry · 2009 · 557 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +13

Charting biologically relevant chemical space: A structural classification of natural products (SCONP)

Мarcus A. Koch, Ansgar Schuffenhauer, Michael Scheck et al. · Proceedings of the National Academy of Sciences · 2005 · 552 citations · Full text

Pharmacy, Chemical Biology, Medicinal Chemistry +12

Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis

Andrea Nören‐Müller, Ivan R. Corrêa, Heino Prinz et al. · Proceedings of the National Academy of Sciences · 2006 · 300 citations · Full text

Pharmacy, Chemical Biology, Medicinal Chemistry +15