Frank J. Dekker

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

Gabriele Siegel, Gregor Obernosterer, Roberto Fiore et al. · Nature Cell Biology · 2009 · 481 citations · Full text

Developmental Biology, Molecular Neuroscience, Dendritic Spine Morphogenesis +8

Small-molecule inhibition of APT1 affects Ras localization and signaling

Frank J. Dekker, Oliver Rocks, Nachiket Vartak et al. · Nature Chemical Biology · 2010 · 393 citations

Signal Transduction, Signaling Pathway, G Protein-coupled Receptor +6

Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing

Bin Liu, Siwei Chen, Anouk La Rose et al. · Nucleic Acids Research · 2019 · 340 citations · Full text

Histone Modifications, Chromatin, Chromatin Compaction +15

Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked

Rosalina Wisastra, Frank J. Dekker · Cancers · 2014 · 187 citations · Full text

Inflammation, Anti-inflammatory, Arachidonic Acid Metabolism +14

Light‐Controlled Histone Deacetylase (HDAC) Inhibitors: Towards Photopharmacological Chemotherapy

Wiktor Szymański, Maria E. Ourailidou, Willem A. Velema et al. · Chemistry - A European Journal · 2015 · 137 citations · Full text