Peter Chase

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

Tsui‐Fen Chou, Steve Brown, Dmitriy Minond et al. · Proceedings of the National Academy of Sciences · 2011 · 323 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Discovery, Synthesis, And Structure-Based Optimization of a Series of <i>N</i>-(<i>tert</i>-Butyl)-2-(<i>N</i>-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou et al. · Journal of Medicinal Chemistry · 2012 · 208 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

Ying Wang, David M. Lonard, Yang Yu et al. · Cancer Research · 2014 · 169 citations

Medicine, Oncology, Pharmacology +17

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Mark Turlington, Aspen Chun, Sakshi Tomar et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 132 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Small Molecule Activators of TRPML3

Christian Grimm, Simone Jörs, S. Adrian Saldanha et al. · Chemistry & Biology · 2010 · 128 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11