S. Adrian Saldanha

Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

Erin M. Bowers, Gai Yan, Chandrani Mukherjee et al. · Chemistry & Biology · 2010 · 641 citations · Full text

P300/cbp Histone Acetyltransferase, Medicinal Chemistry, Drug Target +8

PKA-I Holoenzyme Structure Reveals a Mechanism for cAMP-Dependent Activation

Choel Kim, Cecilia Y. Cheng, S. Adrian Saldanha et al. · Cell · 2007 · 358 citations · Full text

Signal Transduction, Molecular Physiology, Biochemistry +7

Small-molecule proteostasis regulators for protein conformational diseases

Barbara Calamini, Maria Catarina Silva, Franck Madoux et al. · Nature Chemical Biology · 2011 · 224 citations

Protein Function, Protein Folding, Natural Sciences +7

Discovery, Synthesis, And Structure-Based Optimization of a Series of <i>N</i>-(<i>tert</i>-Butyl)-2-(<i>N</i>-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Jon Jacobs, Valerie Grum‐Tokars, Ya Zhou et al. · Journal of Medicinal Chemistry · 2012 · 202 citations · Full text

Molecular Docking, Medicinal Chemistry, Biochemistry +15

Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity

Ivone Gomes, Wakako Fujita, Achla Gupta et al. · Proceedings of the National Academy of Sciences · 2013 · 132 citations · Full text