Erin M. Bowers

Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

Erin M. Bowers, Gai Yan, Chandrani Mukherjee et al. · Chemistry & Biology · 2010 · 641 citations · Full text

P300/cbp Histone Acetyltransferase, Medicinal Chemistry, Drug Target +8

Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor

Brad P. Barnett, Yousang Hwang, Martin S. Taylor et al. · Science · 2010 · 259 citations

Selective Inhibition of p300 HAT Blocks Cell Cycle Progression, Induces Cellular Senescence, and Inhibits the DNA Damage Response in Melanoma Cells

Gai Yan, Mark S. Eller, Courtney M.L. Elm et al. · Journal of Investigative Dermatology · 2013 · 132 citations · Full text

Selective Inhibition, Melanoma, Cellular Senescence +7

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP

Nicholas T. Crump, Catherine A. Hazzalin, Erin M. Bowers et al. · Proceedings of the National Academy of Sciences · 2011 · 110 citations · Full text

Histone Modifications, Histone H3, Epigenetic Change +17

Live‐Cell Studies of p300/CBP Histone Acetyltransferase Activity and Inhibition

Beverley M. Dancy, Nicholas T. Crump, Daniel J. Peterson et al. · ChemBioChem · 2012 · 50 citations · Full text

Molecular Biology, Epigenetics, Cellular Histac Fret +16