Concepedia

Author

Ryan Moslin

Bristol-Myers Squibb (United States)ORCID

Also Known As

R. Moslin, Ryan M. Moslin, Ryan Moslin

11

Publications

828

Citations

6

H-Index

15

Concepts

All Affiliations

Bristol-Myers Squibb (United States)
RM

About

Ryan Moslin is an author at Bristol-Myers Squibb (United States) specializing in innate immunity, chronic inflammatory diseases, and immune regulation.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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21

2

Allergy

1

1

21

3

Immunology

1

1

21

4

Autoimmunity

1

1

21

5

Chronic Inflammation

1

1

21

Ryan Moslin

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6

Publications

815

Citations

6

H-Index

YearCitations

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165

Stephen T. Wrobleski, Ryan Moslin, Shuqun Lin,

Journal of Medicinal Chemistry

2019

345

Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain

James R. Burke, Lihong Cheng, Kathleen M. Gillooly,

Science Translational Medicine

2019

268

Identification of <i>N</i>-Methyl Nicotinamide and <i>N</i>-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)

Ryan Moslin, Yanlei Zhang, Stephen T. Wrobleski,

Journal of Medicinal Chemistry

2019

84

Identification of Imidazo[1,2-<i>b</i>]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors

Chunjian Liu, James C. Lin, Ryan Moslin,

ACS Medicinal Chemistry Letters

2019

49

Identification of imidazo[1,2-<i>b</i>]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling

Ryan Moslin, Daniel S. Gardner, Joseph B. Santella,

MedChemComm

2016

48

349 - BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2, Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease

Jenny Xie, Kathleen M. Gillooly, yifan zhang,

Gastroenterology

2018

21

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