Lihong Cheng

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

Lihong Cheng, Guoliang Ding, Qianhong Qin et al. · Nature Medicine · 2004 · 451 citations

Life Sciences, Cardiology, Physiology +10

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165

Stephen T. Wrobleski, Ryan Moslin, Shuqun Lin et al. · Journal of Medicinal Chemistry · 2019 · 369 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1

Yingli He, Hua She, Ting Zhang et al. · The Journal of Cell Biology · 2017 · 286 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain

James R. Burke, Lihong Cheng, Kathleen M. Gillooly et al. · Science Translational Medicine · 2019 · 282 citations

Life Sciences, Immunology, Pharmacology +14

Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet

Jamie E. Mells, Ping Fu, Shvetank Sharma et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2011 · 199 citations · Full text

Medicine, Endocrinology, Nutrition +17