Glucagon-Like Peptide-1 Receptor Is Present on Human Hepatocytes and Has A Direct Role in Decreasing Hepatic Steatosis in Vitro by Modulating Elements of the Insulin Signaling Pathway

Nitika Gupta, Jamie E. Mells, Richard M. Dunham, +4

Hepatology

GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy

Shvetank Sharma, Jamie E. Mells, Ping Fu, +2

PLoS ONE

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice

Anuradha Rao, Astrid Kosters, Jamie E. Mells, +12

Science Translational Medicine

Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet

Jamie E. Mells, Ping Fu, Shvetank Sharma, +6

American Journal of Physiology-Gastrointestinal and Liver Physiology

NutritionGlp-1 AnalogGlucose ToleranceInsulin SignalingGastrointestinal Peptide Hormone +16

Adiponectin Antagonizes the Oncogenic Actions of Leptin in Hepatocellular Carcinogenesis

Dipali Sharma, Jason Wang, Ping Fu, +8

Hepatology

Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis

Jeffrey A. Handy, Ping Fu, Pradeep Kumar, +4

Biochemical Journal

Multiple MechanismsLeptin SignalsImmunologyHepatic FibrosisGastrointestinal Peptide Hormone +27

Adiponectin activation of AMPK disrupts leptin‐mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS‐3)

Jeffrey A. Handy, Neeraj K. Saxena, Fu Pingping, +4

Journal of Cellular Biochemistry

Ampk DisruptsRecombinant LeptinImmunologyPathologyAdipokines +25

Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis

Jamie E. Mells, Ping Fu, Pradeep Kumar, +3

The Journal of Nutritional Biochemistry

Metabolic SyndromeMetabolic Associated SteatohepatitisMetabolic DisorderMetabolic Associated Steatotic Liver DiseaseNonalcoholic Fatty Liver Disease +12

Adiponectin modulates focal adhesion disassembly in activated hepatic stellate cells: implication for reversing hepatic fibrosis

Pradeep Kumar, T. Lynn Smith, Khalidur Rahman, +4

The FASEB Journal