Irene Bolea

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and <i>N</i>-[(5-(Benzyloxy)-1-methyl-1<i>H</i>-indol-2-yl)methyl]-<i>N</i>-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Irene Bolea, Jordi Juárez‐Jiménez, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2011 · 215 citations · Full text

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Óscar M. Bautista‐Aguilera, Gerard Esteban, Irene Bolea et al. · European Journal of Medicinal Chemistry · 2014 · 136 citations · Full text

Molecular Pharmacology, Neurodegenerative Diseases, Qsar Analysis +11

A Diet Enriched in Polyphenols and Polyunsaturated Fatty Acids, LMN Diet, Induces Neurogenesis in the Subventricular Zone and Hippocampus of Adult Mouse Brain

Tony Valente, Juan Hidalgo, Irene Bolea et al. · Journal of Alzheimer s Disease · 2009 · 97 citations

ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy

José Marco‐Contelles, Mercedes Unzeta, Irene Bolea et al. · Frontiers in Neuroscience · 2016 · 73 citations · Full text

Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s disease

Abdelouahid Samadi, Mourad Chioua, Irene Bolea et al. · European Journal of Medicinal Chemistry · 2011 · 69 citations

Molecular Pharmacology, Neurodegenerative Diseases, Alzheimer's Disease +11