José Marco‐Contelles

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and <i>N</i>-[(5-(Benzyloxy)-1-methyl-1<i>H</i>-indol-2-yl)methyl]-<i>N</i>-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Irene Bolea, Jordi Juárez‐Jiménez, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2011 · 215 citations · Full text

The Effect of a Hydroxy Protecting Group on the PtCl2-Catalyzed Cyclization of Dienynes—A Novel, Efficient, and Selective Synthesis of Carbocycles Acknowledgement is made to the EU for the COST D12 Action “Cascade Free Radical Reactions” and for a short-term scientific mission to Madrid (EM). We thank Nieves Arroyo (CSIC) for preliminary experiments, Dr. J. Vaissermann (UPMC) for the X-ray analysis of 3 e, Dr. M. L. Jimeno (CNQO) for NMR studies on 3 a, Dr. M.-N. Rager (ENSCP) for NMR studies on 3 h, 6, and 11, and Matthieu Bernard (UPMC) for performing some of the experiments. We also thank Dr. Emmanuel Lacôte and Dr. Henri Rudler (UPMC) for helpful discussions.

E. Mainetti, Virginie Mouriès, Louis Fensterbank et al. · Angewandte Chemie International Edition · 2002 · 210 citations

Mechanistic Insights on the Cycloisomerization of Polyunsaturated Precursors Catalyzed by Platinum and Gold Complexes

Elena Soriano, José Marco‐Contelles · Accounts of Chemical Research · 2009 · 192 citations

Novel Organocatalysts, Engineering, Alkene Metathesis +12

Mechanisms of the Transition Metal-Mediated Hydroarylation of Alkynes and Allenes

Elena Soriano, José Marco‐Contelles · Organometallics · 2006 · 151 citations

Theoretical Analysis, Engineering, Macromolecular Engineering +11

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

Li Wang, Gerard Esteban, Masaki Ojima et al. · European Journal of Medicinal Chemistry · 2014 · 137 citations · Full text

Medicinal Chemistry, Neurodegenerative Diseases, Alzheimer's Disease +12