Cristóbal de los Rı́os

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and <i>N</i>-[(5-(Benzyloxy)-1-methyl-1<i>H</i>-indol-2-yl)methyl]-<i>N</i>-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Irene Bolea, Jordi Juárez‐Jiménez, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2011 · 215 citations · Full text

Tacripyrines, the First Tacrine−Dihydropyridine Hybrids, as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

José Marco‐Contelles, Rafael León, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2009 · 134 citations · Full text

Novel Multipotent Tacrine−Dihydropyridine Hybrids with Improved Acetylcholinesterase Inhibitory and Neuroprotective Activities as Potential Drugs for the Treatment of Alzheimer's Disease

José Marco‐Contelles, Rafael León, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2006 · 113 citations · Full text

Combinatorial Chemistry, Acetylcholinesterase Inhibitor, Improved Acetylcholinesterase Inhibitory +19

Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors

José L. Marco, Cristóbal de los Rı́os, Antonio G. Garcı́a et al. · Bioorganic & Medicinal Chemistry · 2004 · 91 citations

Molecular Pharmacology, Biochemistry, Functional Selectivity +11

Synthesis, Inhibitory Activity of Cholinesterases, and Neuroprotective Profile of Novel 1,8-Naphthyridine Derivatives

Cristóbal de los Rı́os, Javier Egea, José Marco‐Contelles et al. · Journal of Medicinal Chemistry · 2010 · 76 citations · Full text

Novel 1,8-Naphthyridine Derivatives, Compound 14, Chemical Biology +18