Rafael León

Catalytic enantioselective assembly of complex molecules containing embedded quaternary stereogenic centres from simple anisidine derivatives

Rafael León, Anup M. Jawalekar, Thomas Redert et al. · Chemical Science · 2011 · 135 citations

Engineering, Organic Chemistry, Quaternary Stereogenic Centres +16

Tacripyrines, the First Tacrine−Dihydropyridine Hybrids, as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

José Marco‐Contelles, Rafael León, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2009 · 134 citations · Full text

The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation

Alejandra Romero, Álvaro San Hipólito‐Luengo, Laura A. Villalobos et al. · Aging Cell · 2019 · 118 citations · Full text

Novel Multipotent Tacrine−Dihydropyridine Hybrids with Improved Acetylcholinesterase Inhibitory and Neuroprotective Activities as Potential Drugs for the Treatment of Alzheimer's Disease

José Marco‐Contelles, Rafael León, Cristóbal de los Rı́os et al. · Journal of Medicinal Chemistry · 2006 · 113 citations · Full text

Combinatorial Chemistry, Acetylcholinesterase Inhibitor, Improved Acetylcholinesterase Inhibitory +19

Neuroprotective effect of melatonin against ischemia is partially mediated by alpha‐7 nicotinic receptor modulation and<scp>HO</scp>‐1 overexpression

Esther Parada, Izaskun Buendía, Rafael León et al. · Journal of Pineal Research · 2013 · 106 citations