Óscar M. Bautista‐Aguilera

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Óscar M. Bautista‐Aguilera, Gerard Esteban, Irene Bolea et al. · European Journal of Medicinal Chemistry · 2014 · 141 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

Li Wang, Gerard Esteban, Masaki Ojima et al. · European Journal of Medicinal Chemistry · 2014 · 138 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

The Antioxidant Additive Approach for Alzheimer’s Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators

Mohamed Benchekroun, Alejandro Romero, Javier Egea et al. · Journal of Medicinal Chemistry · 2016 · 102 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H₃R Antagonism for Neurodegenerative Diseases

Óscar M. Bautista‐Aguilera, Stefanie Hagenow, Alejandra Palomino‐Antolín et al. · Angewandte Chemie International Edition · 2017 · 101 citations

Medicine, Medicinal Chemistry, Pharmacology +17

<i>N</i>-Methyl-<i>N</i>-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1<i>H</i>-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor

Óscar M. Bautista‐Aguilera, Abdelouahid Samadi, Mourad Chioua et al. · Journal of Medicinal Chemistry · 2014 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17