Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and <i>N</i>-[(5-(Benzyloxy)-1-methyl-1<i>H</i>-indol-2-yl)methyl]-<i>N</i>-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Irene Bolea, Jordi Juárez‐Jiménez, Cristóbal de los Rı́os, +6

Journal of Medicinal Chemistry

Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H₃R Antagonism for Neurodegenerative Diseases

Óscar M. Bautista‐Aguilera, Stefanie Hagenow, Alejandra Palomino‐Antolín, +18

Angewandte Chemie International Edition

Synthesis and biological evaluation of 3,6-diamino-1H-pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors

Mourad Chioua, Abdelouahid Samadi, Elena Soriano, +3

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryMedicineNatural SciencesProtein Kinase Inhibitors +7

Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

Emna Maalej, Fakher Chabchoub, María Jesús Oset‐Gasque, +12

European Journal of Medicinal Chemistry

Medicinal ChemistryPotential DrugsBiochemistryNatural SciencesMedicine +7

Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s disease

Abdelouahid Samadi, Mourad Chioua, Irene Bolea, +8

European Journal of Medicinal Chemistry

Molecular PharmacologyNeurodegenerative DiseasesAlzheimer's DiseaseNew Multipotent MaoMedicine +9

Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

Abdelouahid Samadi, Cristóbal de los Rı́os, Irene Bolea, +9

European Journal of Medicinal Chemistry

Alzheimer's DiseaseMedicineDementiaPharmacological AgentNeuropharmacology +11

α-Aryl-<i>N</i>-alkyl Nitrones, as Potential Agents for Stroke Treatment: Synthesis, Theoretical Calculations, Antioxidant, Anti-inflammatory, Neuroprotective, and Brain–Blood Barrier Permeability Properties

Mourad Chioua, David Sucunza, Elena Soriano, +9

Journal of Medicinal Chemistry

Cerebral Vascular RegulationOxidative StressNeuroinflammationMedicinal ChemistryBbb Penetration +15

<i>N</i>-Methyl-<i>N</i>-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1<i>H</i>-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase Dual Inhibitor

Óscar M. Bautista‐Aguilera, Abdelouahid Samadi, Mourad Chioua, +11

Journal of Medicinal Chemistry

Combinatorial ChemistryMolecular PharmacologyMedicinal ChemistryNew CholinesteraseNew Indole Derivatives +12

Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling

Abdelouahid Samadi, Martín Estrada, Concepción Pérez, +5

European Journal of Medicinal Chemistry

Medicinal ChemistryNeurodegenerative DiseasesAlzheimer's DiseasePotential DrugsMedicine +10

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer&amp;rsquo;s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids

José Marco-Contelles, Óscar M. Bautista‐Aguilera, Gerard Esteban, +8

Drug Design Development and Therapy

Dphs 13Neurochemical BiomarkersPharmacotherapyPharmaceutical ChemistryPre-clinical Pharmacology +19