Gerard Esteban

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

Li Wang, Gerard Esteban, Masaki Ojima et al. · European Journal of Medicinal Chemistry · 2014 · 137 citations · Full text

Medicinal Chemistry, Neurodegenerative Diseases, Alzheimer's Disease +12

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Óscar M. Bautista‐Aguilera, Gerard Esteban, Irene Bolea et al. · European Journal of Medicinal Chemistry · 2014 · 136 citations · Full text

Molecular Pharmacology, Neurodegenerative Diseases, Qsar Analysis +11

Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation

Mingyu Wu, Gerard Esteban, Simone Brogi et al. · European Journal of Medicinal Chemistry · 2015 · 100 citations · Full text

Combinatorial Chemistry, Medicine, Donepezil-like Multifunctional Agents +5

ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy

José Marco‐Contelles, Mercedes Unzeta, Irene Bolea et al. · Frontiers in Neuroscience · 2016 · 73 citations · Full text

Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s disease

Abdelouahid Samadi, Mourad Chioua, Irene Bolea et al. · European Journal of Medicinal Chemistry · 2011 · 69 citations

Molecular Pharmacology, Neurodegenerative Diseases, Alzheimer's Disease +11