Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases

Margherita Brindisi, A. Prasanth Saraswati, Simone Brogi, +3

Journal of Medicinal Chemistry

Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation

Mingyu Wu, Gerard Esteban, Simone Brogi, +7

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicineDonepezil-like Multifunctional AgentsPharmacologyMolecular Modeling +3

Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain

Margherita Brindisi, Samuele Maramai, Sandra Gemma, +24

Journal of Medicinal Chemistry

NeuropeptidesPain MedicineCompound 4AMolecular PainPharmacotherapy +18

The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

Lara Testai, Eugenia Piragine, Ilaria Piano, +14

Oxidative Medicine and Cellular Longevity

Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking

Margherita Brindisi, Simone Brogi, Nicola Relitti, +10

Scientific Reports

Computational Tool for Fast in silico Evaluation of hERG K+ Channel Affinity

Giulia Chemi, Sandra Gemma, Giuseppe Campiani, +3

Frontiers in Chemistry

Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G Protein-Coupled Prokineticin Receptor-1

Adeline Gasser, Simone Brogi, Kyoji Urayama, +6

PLoS ONE

High ThroughputCardiovascular PharmacologyPharmacotherapyCalcium ReleaseGastrointestinal Peptide Hormone +18

Mimicking the Intramolecular Hydrogen Bond: Synthesis, Biological Evaluation, and Molecular Modeling of Benzoxazines and Quinazolines as Potential Antimalarial Agents

Sandra Gemma, Caterina Camodeca, Margherita Brindisi, +21

Journal of Medicinal Chemistry

Combinatorial ChemistryBioorganic ChemistryAntiparasitic AgentMalariaOrganic Chemistry +15

Verbascoside Inhibits Promastigote Growth and Arginase Activity of <i>Leishmania amazonensis</i>

Claudia do Carmo Maquiaveli, João Francisco Lucon-Júnior, Simone Brogi, +4

Journal of Natural Products

Antiparasitic AgentVisceral LeishmaniasisParasite GenomicsMolecular PharmacologyMedicinal Chemistry +15

Resveratrol-like Compounds as SIRT1 Activators

Lidia Ciccone, Eugenia Piragine, Simone Brogi, +6

International Journal of Molecular Sciences