Joshua Murtie

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Katya Marjon, Michael J. Cameron, Phong Quang et al. · Cell Reports · 2016 · 447 citations · Full text

Medicine, Cancer Biology, Oncology +17

Presenilin-Dependent ErbB4 Nuclear Signaling Regulates the Timing of Astrogenesis in the Developing Brain

S. Pablo Sardi, Joshua Murtie, Samir Koirala et al. · Cell · 2006 · 344 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders

Kristine Roy, Joshua Murtie, Bassem F. El‐Khodor et al. · Proceedings of the National Academy of Sciences · 2007 · 311 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Zainab Jagani, E. Lorena Mora‐Blanco, Courtney G. Sansam et al. · Nature Medicine · 2010 · 253 citations

Life Sciences, Genetics, Molecular Biology +14

MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage

Peter Kalev, Marc L. Hyer, Zenon Konteatis et al. · Cancer Cell · 2021 · 234 citations

Life Sciences, Molecular Biology, Oncology +7