Joshua Murtie

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Katya Marjon, Michael J. Cameron, Phong Quang et al. · Cell Reports · 2016 · 415 citations · Full text

Presenilin-Dependent ErbB4 Nuclear Signaling Regulates the Timing of Astrogenesis in the Developing Brain

S. Pablo Sardi, Joshua Murtie, Samir Koirala et al. · Cell · 2006 · 343 citations · Full text

Developmental Biology, Ependyma, Developmental Cognitive Neuroscience +9

Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders

Kristine Roy, Joshua Murtie, Bassem F. El‐Khodor et al. · Proceedings of the National Academy of Sciences · 2007 · 308 citations · Full text

Neuropsychology, Neuropsychiatric Disorders, Clinical Neuroscience +19

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Zainab Jagani, E. Lorena Mora‐Blanco, Courtney G. Sansam et al. · Nature Medicine · 2010 · 252 citations · Full text

Signaling Pathway, Medicine, Pathology +8

MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage

Peter Kalev, Marc L. Hyer, Zenon Konteatis et al. · Cancer Cell · 2021 · 214 citations

Medicine, Cancer Growth, Cancer Cell Biology +9