Karl F. Blom

MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products

John V. Duncia, Joseph B. Santella, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 404 citations · Full text

Biological Activity, Mek Inhibitors, Medicinal Chemistry +12

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Andrew P. Combs, Eddy W. Yue, Michael J. Bower et al. · Journal of Medicinal Chemistry · 2005 · 101 citations · Full text

Molecular Docking, Crystal Structure, Medicinal Chemistry +13

Assay Miniaturization for Ultra-High Throughput Screening of Combinatorial and Discrete Compound Libraries: A 9600-Well (0.2 Microliter) Assay System

Kevin R. Oldenburg, Ji-Hu Zhang, Tongming Chen et al. · SLAS DISCOVERY · 1998 · 73 citations · Full text

Estimating the Precision of Exact Mass Measurements on an Orthogonal Time-of-Flight Mass Spectrometer

Karl F. Blom · Analytical Chemistry · 2001 · 61 citations

Engineering, Measurement, Complex Mixtures +24

Determining Affinity-Selected Ligands and Estimating Binding Affinities by Online Size Exclusion Chromatography/Liquid Chromatography−Mass Spectrometry

Karl F. Blom, Barbara S. Larsen, Charles N. McEwen · Journal of Combinatorial Chemistry · 1998 · 56 citations